No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
831 |
6. Filter based on genotype QC (FinnGen only) |
766 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Syphilis based on the number of shared cases.
Similar with more cases:
- Infections with a predominantly sexual mode of transmission
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 6496 | 2541 | 3811 |
Only index persons | 5450 | 2193 | 3257 |
Unadjusted period prevalence (%) | |||
Whole population | 0.09 | 0.07 | 0.11 |
Only index persons | 0.11 | 0.08 | 0.12 |
Median age at first event (years) | |||
Whole population | 46.90 | 46.69 | 47.41 |
Only index persons | 45.30 | 44.04 | 46.15 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 766 | 258 | 508 |
Unadjusted period prevalence (%) | 0.20 | 0.10 | 0.26 |
Median age at first event (years) | 47.14 | 45.62 | 47.91 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint AB1_SYPHILIS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_SYPHILIS | 2.438 [2.02, 2.94] | < 0.001 |
Birth year | 0.998 [0.99, 1.01] | 0.586 |
During the follow-up period (1.1.1998 — 31.12.2019), 373 out of 1614 females with AB1_SYPHILIS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_SYPHILIS | 2.499 [2.1, 2.98] | < 0.001 |
Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 561 out of 2476 males with AB1_SYPHILIS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_SYPHILIS.N-year risk | Females | Males |
---|---|---|
1 | 0.115% | 0.567% |
5 | 1.038% | 3.026% |
10 | 3.365% | 7.243% |
15 | 6.756% | 13.391% |
20 | 12.396% | 22.162% |
Relationships between endpoints
↥Index endpoint: AB1_SYPHILIS – Syphilis
GWS hits: -