No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
376 |
4. Check minimum number of eventsNone |
376 |
5. Include endpointsNone |
376 |
6. Filter based on genotype QC (FinnGen only) |
344 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Early syphilis based on the number of shared cases.
Similar with more cases:
- Syphilis
- Infections with a predominantly sexual mode of transmission
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2515 | 815 | 1643 |
Only index persons | 2222 | 742 | 1480 |
Unadjusted period prevalence (%) | |||
Whole population | 0.04 | 0.02 | 0.05 |
Only index persons | 0.05 | 0.03 | 0.06 |
Median age at first event (years) | |||
Whole population | 36.88 | 33.67 | 38.63 |
Only index persons | 36.48 | 32.83 | 38.31 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 344 | 82 | 262 |
Unadjusted period prevalence (%) | 0.11 | 0.03 | 0.13 |
Median age at first event (years) | 39.42 | 31.45 | 41.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint AB1_EARLY_SYPHILIS and mortality.
Females
No dataMales
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_EARLY_SYPHILIS | 1.498 [1.19, 1.88] | < 0.001 |
Birth year | 0.983 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 997 males with AB1_EARLY_SYPHILIS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_EARLY_SYPHILIS.N-year risk | Females | Males |
---|---|---|
1 | No data | 0.299% |
5 | No data | 1.658% |
10 | No data | 4.176% |
15 | No data | 7.743% |
20 | No data | 12.609% |
Relationships between endpoints
↥Index endpoint: AB1_EARLY_SYPHILIS – Early syphilis
GWS hits: -