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Other parasitologically confirmed or unspecified malaria

Endpoint Browser PheWeb

AB1_MALARIA_NOS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B53, B54
  • Hospital discharge: ICD-9 — 08[4]
  • Hospital discharge: ICD-8 — 08[4]
  • Hospital discharge: excluded ICD-9 — 084[0-1]
  • Hospital discharge: excluded ICD-8 — 084[0-1]
  • Cause of death: ICD-10 — B53, B54
  • Cause of death: ICD-9 — 08[4]
  • Cause of death: ICD-8 — 08[4]
  • Cause of death: excluded ICD-9 — 084[0-1]
  • Cause of death: excluded ICD-8 — 084[0-1]

2 out of 7 registries used, show all original rules.

74

4. Check minimum number of events

None

74

5. Include endpoints

None

74

6. Filter based on genotype QC (FinnGen only)

63

Control definitions (FinnGen only)

Control exclude AB1_PROTOZOAL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1013 379 602
Only index persons 891 349 542
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.01 0.02
Median age at first event (years)
Whole population 33.83 31.03 35.70
Only index persons 34.17 31.81 35.70

-FinnGen-

Key figures

All Female Male
Number of individuals 63 31 32
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 36.93 34.30 39.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

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Association

Association between endpoint AB1_MALARIA_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_MALARIA_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

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Index endpoint: AB1_MALARIA_NOS – Other parasitologically confirmed or unspecified malaria

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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