No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
222 |
4. Check minimum number of eventsNone |
222 |
5. Include endpointsNone |
222 |
6. Filter based on genotype QC (FinnGen only) |
214 |
Control definitions (FinnGen only)
Control exclude
LUNG_TRANSPLANTATION
Extra metadata
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Lung transplant status
based on the number of shared cases.
Similar with more cases:
- Transplanted organ and tissue status
- Persons with potential health hazards related to family and personal history and certain conditions influencing health status
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 624 | 258 | 366 |
| Only index persons | 563 | 236 | 327 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 54.70 | 58.10 |
| Only index persons | 56.77 | 54.70 | 58.26 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 214 | 85 | 129 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 55.98 | 52.03 | 58.58 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint Z21_LUNG_TRANSPLANT_STATUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Z21_LUNG_TRANSPLANT_STATUS | 6.846 [4.54, 10.33] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.826 |
During the follow-up period (1.1.1998 — 31.12.2019), 72 out of 230 females with Z21_LUNG_TRANSPLANT_STATUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Z21_LUNG_TRANSPLANT_STATUS | 5.555 [3.49, 8.85] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 314 males with Z21_LUNG_TRANSPLANT_STATUS died.
Mortality risk
Mortality risk for people of age
years, who have Z21_LUNG_TRANSPLANT_STATUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.828% | 1.106% |
| 5 | 4.172% | 6.44% |
| 10 | 11.641% | 15.219% |
| 15 | 20.622% | 26.458% |
| 20 | 34.009% | 41.682% |
Relationships between endpoints
↥Index endpoint: Z21_LUNG_TRANSPLANT_STATUS – Lung transplant status
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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