No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
223 |
6. Filter based on genotype QC (FinnGen only) |
215 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Lung transplantation
based on the number of shared cases.
Similar with more cases:
- Factors influencing health status and contact with health services
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 635 | 264 | 371 |
| Only index persons | 569 | 239 | 330 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 54.38 | 58.17 |
| Only index persons | 56.75 | 54.62 | 58.30 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 215 | 86 | 129 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 55.76 | 51.52 | 58.58 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint LUNG_TRANSPLANTATION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| LUNG_TRANSPLANTATION | 7.063 [4.68, 10.65] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.283 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 232 females with LUNG_TRANSPLANTATION died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| LUNG_TRANSPLANTATION | 5.555 [3.44, 8.97] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 318 males with LUNG_TRANSPLANTATION died.
Mortality risk
Mortality risk for people of age
years, who have LUNG_TRANSPLANTATION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.661% | 1.124% |
| 5 | 4.172% | 5.833% |
| 10 | 10.491% | 13.793% |
| 15 | 18.406% | 24.477% |
| 20 | 29.987% | 38.464% |
Relationships between endpoints
↥Index endpoint: LUNG_TRANSPLANTATION – Lung transplantation
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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