No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1735 |
4. Check minimum number of eventsNone |
1735 |
5. Include endpointsNone |
1735 |
6. Filter based on genotype QC (FinnGen only) |
1650 |
Control definitions (FinnGen only)
Control exclude
DM_NEPHROPATHY
Extra metadata
Level in the ICD hierarchy
4
Special
KIDNEY_TRANSPLANT
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z94
Similar endpoints
↥List of similar endpoints to
Kidney transplant status
based on the number of shared cases.
Similar with more cases:
- Transplanted organ and tissue status
- Persons with potential health hazards related to family and personal history and certain conditions influencing health status
- Factors influencing health status and contact with health services
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6739 | 2558 | 4131 |
| Only index persons | 5823 | 2232 | 3591 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.07 | 0.12 |
| Only index persons | 0.12 | 0.08 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 52.22 | 52.03 | 52.31 |
| Only index persons | 52.02 | 51.62 | 52.27 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1650 | 657 | 993 |
| Unadjusted period prevalence (%) | 0.40 | 0.26 | 0.50 |
| Median age at first event (years) | 50.96 | 49.51 | 51.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint Z21_KIDNEY_TRANSPLANT_STATUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Z21_KIDNEY_TRANSPLANT_STATUS | 5.05 [4.4, 5.8] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.126 |
During the follow-up period (1.1.1998 — 31.12.2019), 688 out of 2173 females with Z21_KIDNEY_TRANSPLANT_STATUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Z21_KIDNEY_TRANSPLANT_STATUS | 3.794 [3.41, 4.23] | < 0.001 |
| Birth year | 0.981 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1255 out of 3532 males with Z21_KIDNEY_TRANSPLANT_STATUS died.
Mortality risk
Mortality risk for people of age
years, who have Z21_KIDNEY_TRANSPLANT_STATUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.657% | 0.594% |
| 5 | 3.099% | 3.493% |
| 10 | 7.124% | 8.19% |
| 15 | 12.824% | 16.623% |
| 20 | 21.575% | 26.84% |
Relationships between endpoints
↥Index endpoint: Z21_KIDNEY_TRANSPLANT_STATUS – Kidney transplant status
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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