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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Systemic sclerosis induced by drugs and chemicals

SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M34.2#

1 out of 7 registries used, show all original rules.

9

4. Check minimum number of events

None

9

5. Include endpoints

None

9

6. Filter based on genotype QC (FinnGen only)

9

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 46 28 17
Only index persons 43 26 17
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 57.05 55.83 58.34
Only index persons 56.57 55.41 58.34

-FinnGen-

Key figures

All Female Male
Number of individuals 9 6 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 50.59 48.98 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: SYSTEMIC_SCLEROSIS_INDUCED_DRUGS_CHEMIC – Systemic sclerosis induced by drugs and chemicals

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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