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This is a non-core endpoint: only basic statistics are computed.

Fracture of lower limb, level unspecified

ST19_FRACT_LOWER_LIMB_LEVEL_UNSPE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 T12
  • Cause of death: ICD-10 T12

2 out of 7 registries used, show all original rules.

16

4. Check minimum number of events

None

16

5. Include endpoints

None

16

6. Filter based on genotype QC (FinnGen only)

14

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 T0[8-9]|T1[0-4]
Name in latin Fractura membri inferioris, regione non specificata

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 233 102 129
Only index persons 209 92 117
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 43.84 53.11 36.34
Only index persons 43.66 53.11 36.23

-FinnGen-

Key figures

All Female Male
Number of individuals 14 5 9
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 43.56 41.78 44.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint ST19_FRACT_LOWER_LIMB_LEVEL_UNSPE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have ST19_FRACT_LOWER_LIMB_LEVEL_UNSPE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: ST19_FRACT_LOWER_LIMB_LEVEL_UNSPE – Fracture of lower limb, level unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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