No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersCheck mode of ICD-10 codes: %J300 Registry filters: 2 out of 7 registries used, show all original rules. |
2560 |
4. Check minimum number of eventsNone |
2560 |
5. Include endpointsNone |
2560 |
6. Filter based on genotype QC (FinnGen only) |
2479 |
Control definitions (FinnGen only)
Control exclude
ASTHMA_NOS
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Vasomotor rhinitis (mode)
based on the number of shared cases.
Similar with more cases:
- Vasomotor and allergic rhinitis
- Other diseases of upper respiratory tract
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18772 | 10965 | 7751 |
| Only index persons | 18144 | 10727 | 7417 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.31 | 0.22 |
| Only index persons | 0.35 | 0.39 | 0.28 |
| Median age at first event (years) | |||
| Whole population | 46.83 | 47.11 | 46.47 |
| Only index persons | 46.74 | 47.05 | 46.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2479 | 1575 | 904 |
| Unadjusted period prevalence (%) | 0.56 | 0.62 | 0.45 |
| Median age at first event (years) | 50.70 | 48.51 | 54.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint RHINITIS_VASOMOTOR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| RHINITIS_VASOMOTOR | 0.877 [0.78, 0.98] | 0.021 |
| Birth year | 0.999 [0.99, 1.01] | 0.818 |
During the follow-up period (1.1.1998 — 31.12.2019), 736 out of 10047 females with RHINITIS_VASOMOTOR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| RHINITIS_VASOMOTOR | 0.866 [0.77, 0.97] | 0.011 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 835 out of 7091 males with RHINITIS_VASOMOTOR died.
Mortality risk
Mortality risk for people of age
years, who have RHINITIS_VASOMOTOR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.106% | 0.16% |
| 5 | 0.563% | 0.996% |
| 10 | 1.343% | 2.368% |
| 15 | 2.626% | 4.437% |
| 20 | 4.741% | 7.455% |
Relationships between endpoints
↥Index endpoint: RHINITIS_VASOMOTOR – Vasomotor rhinitis (mode)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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