info icon

Congenital malformations of aortic and mitral valves

Q17_CONGEN_MALFO_AORTIC_MITRAL_VALVES

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q23
  • Cause of death: ICD-10 Q23

2 out of 7 registries used, show all original rules.

1355

4. Check minimum number of events

None

1355

5. Include endpoints

None

1355

6. Filter based on genotype QC (FinnGen only)

1301

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Parent code in ICD-10 Q2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1301 439 862
Unadjusted period prevalence (%) 0.35 0.17 0.43
Median age at first event (years) 51.16 47.67 52.93

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Q17_CONGEN_MALFO_AORTIC_MITRAL_VALVES – Congenital malformations of aortic and mitral valves

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).