No definition available.
Infections specific to the perinatal period
P16_INFECTIONS_SPECIFIC_PERINA_PERIOD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
384 |
4. Check minimum number of eventsNone |
384 |
5. Include endpoints |
384 |
6. Filter based on genotype QC (FinnGen only) |
365 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P
Name in latin
Infectiones temporis perinatalis specificae
Infections specific to the perinatal period
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 42413 | 17614 | 24798 |
| Only index persons | 19844 | 8095 | 11749 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.61 | 0.50 | 0.69 |
| Only index persons | 0.39 | 0.30 | 0.45 |
| Median age at first event (years) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 365 | 201 | 164 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.08 |
| Median age at first event (years) | 0.00 | 0.00 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint P16_INFECTIONS_SPECIFIC_PERINA_PERIOD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_INFECTIONS_SPECIFIC_PERINA_PERIOD | 1.84 [1.45, 2.34] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.613 |
During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 16734 females with P16_INFECTIONS_SPECIFIC_PERINA_PERIOD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_INFECTIONS_SPECIFIC_PERINA_PERIOD | 1.099 [0.9, 1.34] | 0.351 |
| Birth year | 0.987 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 113 out of 23642 males with P16_INFECTIONS_SPECIFIC_PERINA_PERIOD died.
Mortality risk
Mortality risk for people of age
years, who have P16_INFECTIONS_SPECIFIC_PERINA_PERIOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.158% | 0.199% |
| 5 | 1.081% | 1.32% |
| 10 | 2.695% | 3.159% |
| 15 | 5.399% | 6.062% |
| 20 | 9.582% | 10.507% |
Relationships between endpoints
↥Index endpoint: P16_INFECTIONS_SPECIFIC_PERINA_PERIOD – Infections specific to the perinatal period
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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