bacteriemia: An infectious disease caused by bacteria causing sepsis.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
185 |
4. Check minimum number of eventsNone |
185 |
5. Include endpointsNone |
185 |
6. Filter based on genotype QC (FinnGen only) |
177 |
Control definitions (FinnGen only)
Control exclude
P16_INFECTIONS_SPECIFIC_PERINA_PERIOD
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P3
Name in latin
Sepsis bacterialis neonatorum
Similar endpoints
↥List of similar endpoints to
Bacterial sepsis of newborn
based on the number of shared cases.
Similar with more cases:
- Infections specific to the perinatal period
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 26986 | 11234 | 15752 |
| Only index persons | 10206 | 4214 | 5992 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.39 | 0.32 | 0.44 |
| Only index persons | 0.20 | 0.15 | 0.23 |
| Median age at first event (years) | |||
| Whole population | - | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 177 | 98 | 79 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 0.00 | 0.00 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint P16_BACTERIAL_SEPSIS_NEWBO and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_BACTERIAL_SEPSIS_NEWBO | 1.309 [1.03, 1.66] | 0.027 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 75 out of 15045 males with P16_BACTERIAL_SEPSIS_NEWBO died.
Mortality risk
Mortality risk for people of age
years, who have P16_BACTERIAL_SEPSIS_NEWBO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.274% |
| 5 | No data | 1.604% |
| 10 | No data | 3.955% |
| 15 | No data | 7.652% |
| 20 | No data | 12.738% |
Relationships between endpoints
↥Index endpoint: P16_BACTERIAL_SEPSIS_NEWBO – Bacterial sepsis of newborn
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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