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This is a non-core endpoint: only basic statistics are computed.

Fetus and newborn affected by maternal use of alcohol

P16_FET_NEWB_MATERN_USE_ALCOHOL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P04.3
  • Hospital discharge: ICD-9 7607A
  • Cause of death: ICD-10 P04.3
  • Cause of death: ICD-9 7607A

2 out of 7 registries used, show all original rules.

12

4. Check minimum number of events

None

12

5. Include endpoints

None

12

6. Filter based on genotype QC (FinnGen only)

12

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
Special FETUSALCO
First used in FinnGen datafreeze DF4
Parent code in ICD-10 P04
Name in latin Fetus et neonatus usu alcohol matris affectus

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 659 317 341
Only index persons 407 198 209
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 0.33 0.27 0.27
Only index persons 0.87 0.83 0.90

-FinnGen-

Key figures

All Female Male
Number of individuals 12 8 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 0.88 0.23 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint P16_FET_NEWB_MATERN_USE_ALCOHOL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_MATERN_USE_ALCOHOL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FET_NEWB_MATERN_USE_ALCOHOL – Fetus and newborn affected by maternal use of alcohol

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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