No definition available.
Cardiovascular disorders originating in the perinatal period
P16_CARDIOV_DISORD_ORIGINA_PERINA_PERIOD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
124 |
4. Check minimum number of eventsNone |
124 |
5. Include endpointsNone |
124 |
6. Filter based on genotype QC (FinnGen only) |
111 |
Control definitions (FinnGen only)
Control exclude
P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P2
Name in latin
Morbositates cardiovasculares origine perinatales
Similar endpoints
↥List of similar endpoints to
Cardiovascular disorders originating in the perinatal period
based on the number of shared cases.
Similar with more cases:
- Respiratory and cardiovascular disorders specific to the perinatal period
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7884 | 3729 | 4154 |
| Only index persons | 4035 | 1874 | 2161 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.11 | 0.12 |
| Only index persons | 0.08 | 0.07 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.01 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 111 | 63 | 48 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 0.00 | 0.00 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint P16_CARDIOV_DISORD_ORIGINA_PERINA_PERIOD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_CARDIOV_DISORD_ORIGINA_PERINA_PERIOD | 8.691 [4.36, 17.33] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.094 |
During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 3415 females with P16_CARDIOV_DISORD_ORIGINA_PERINA_PERIOD died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have P16_CARDIOV_DISORD_ORIGINA_PERINA_PERIOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.626% | No data |
| 5 | 4.213% | No data |
| 10 | 11.306% | No data |
| 15 | 21.689% | No data |
| 20 | 35.607% | No data |
Relationships between endpoints
↥Index endpoint: P16_CARDIOV_DISORD_ORIGINA_PERINA_PERIOD – Cardiovascular disorders originating in the perinatal period
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data