asphyxia neonatorum: Respiratory failure in the newborn. (Dorland, 27th ed)
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
168 |
4. Check minimum number of eventsNone |
168 |
5. Include endpointsNone |
168 |
6. Filter based on genotype QC (FinnGen only) |
157 |
Control definitions (FinnGen only)
Control exclude
P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P2
Name in latin
Asphyxia intra partum
Similar endpoints
↥List of similar endpoints to
Birth asphyxia
based on the number of shared cases.
Similar with more cases:
- Respiratory and cardiovascular disorders specific to the perinatal period
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13251 | 5713 | 7536 |
| Only index persons | 7432 | 3138 | 4294 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.16 | 0.21 |
| Only index persons | 0.14 | 0.12 | 0.16 |
| Median age at first event (years) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 157 | 87 | 70 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.04 |
| Median age at first event (years) | 0.00 | 0.00 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint P16_BIRTH_ASPHYXIA and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_BIRTH_ASPHYXIA | 2.191 [1.71, 2.8] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.038 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 6809 males with P16_BIRTH_ASPHYXIA died.
Mortality risk
Mortality risk for people of age
years, who have P16_BIRTH_ASPHYXIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.517% |
| 5 | No data | 2.843% |
| 10 | No data | 7.153% |
| 15 | No data | 12.962% |
| 20 | No data | 22.039% |
Relationships between endpoints
↥Index endpoint: P16_BIRTH_ASPHYXIA – Birth asphyxia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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