No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4833 |
4. Check minimum number of eventsNone |
4833 |
5. Include endpointsNone |
4833 |
6. Filter based on genotype QC (FinnGen only) |
4617 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Poor fetal growth
based on the number of shared cases.
Similar with more cases:
- Pre-eclampsia or poor fetal growth
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 42702 | 42702 | - |
| Only index persons | 42233 | 42233 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.22 | 1.22 | - |
| Only index persons | 1.55 | 1.55 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.46 | - |
| Only index persons | - | 29.43 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4617 | 4617 | - |
| Unadjusted period prevalence (%) | 1.81 | 1.81 | - |
| Median age at first event (years) | 30.28 | 30.28 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint O15_POOR_FETGRO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_POOR_FETGRO | 1.13 [0.96, 1.34] | 0.154 |
| Birth year | 0.994 [0.99, 1.0] | 0.179 |
During the follow-up period (1.1.1998 — 31.12.2019), 262 out of 33445 females with O15_POOR_FETGRO died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_POOR_FETGRO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.141% | No data |
| 5 | 0.614% | No data |
| 10 | 1.52% | No data |
| 15 | 3.059% | No data |
| 20 | 5.523% | No data |
Relationships between endpoints
↥Index endpoint: O15_POOR_FETGRO – Poor fetal growth
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data