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Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

DOID EFO Endpoint Browser PheWeb

N14_VAGINITIS

vulvovaginitis: Inflammation of the VULVA and the VAGINA, characterized by discharge, burning, and PRURITUS.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N76.0, N76.1, N76.2, N76.3, N76.4
  • Hospital discharge: ICD-9 — 6161
  • Hospital discharge: ICD-8 — 6221
  • Cause of death: ICD-10 — N76.0, N76.1, N76.2, N76.3, N76.4
  • Cause of death: ICD-9 — 6161
  • Cause of death: ICD-8 — 6221

2 out of 7 registries used, show all original rules.

6677

4. Check minimum number of events

None

6677

5. Include endpoints

None

6677

6. Filter based on genotype QC (FinnGen only)

6384

Control definitions (FinnGen only)

Control exclude N14_FEMALEGENINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 46490 46490 -
Only index persons 43588 43588 -
Unadjusted period prevalence (%)
Whole population 1.33 1.33 -
Only index persons 1.60 1.60 -
Median age at first event (years)
Whole population - 34.64 -
Only index persons - 34.07 -

-FinnGen-

Key figures

All Female Male
Number of individuals 6384 6384 -
Unadjusted period prevalence (%) 2.51 2.51 -
Median age at first event (years) 37.44 37.44 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint N14_VAGINITIS and mortality.

Females

Parameter HR [95% CI] p-value
N14_VAGINITIS 1.15 [1.02, 1.3] 0.026
Birth year 0.992 [0.98, 1.0] 0.075

During the follow-up period (1.1.1998 — 31.12.2019), 1781 out of 25714 females with N14_VAGINITIS died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VAGINITIS.

N-year risk Females Males
1 0.089% No data
5 0.707% No data
10 1.627% No data
15 3.044% No data
20 5.569% No data

Relationships between endpoints

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Index endpoint: N14_VAGINITIS – Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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