urethritis: Inflammation of the urethra.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
790 |
4. Check minimum number of eventsNone |
790 |
5. Include endpointsNone |
790 |
6. Filter based on genotype QC (FinnGen only) |
741 |
Control definitions (FinnGen only)
Control exclude
N14_URINOTH
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N30-N39
Name in latin
Urethritis et syndroma urethrale
Urethritis and urethral syndrome
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7952 | 4797 | 3097 |
| Only index persons | 6830 | 4132 | 2698 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.14 | 0.09 |
| Only index persons | 0.13 | 0.15 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 41.23 | 46.64 | 32.80 |
| Only index persons | 38.67 | 43.51 | 31.27 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 741 | 485 | 256 |
| Unadjusted period prevalence (%) | 0.17 | 0.19 | 0.13 |
| Median age at first event (years) | 42.00 | 44.21 | 37.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint N14_URETHRITISANDURSYNDR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_URETHRITISANDURSYNDR | 1.345 [1.17, 1.54] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.536 |
During the follow-up period (1.1.1998 — 31.12.2019), 608 out of 3107 females with N14_URETHRITISANDURSYNDR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_URETHRITISANDURSYNDR | 1.552 [1.27, 1.89] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 327 out of 1942 males with N14_URETHRITISANDURSYNDR died.
Mortality risk
Mortality risk for people of age
years, who have N14_URETHRITISANDURSYNDR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.172% | 0.323% |
| 5 | 0.933% | 1.761% |
| 10 | 2.163% | 4.378% |
| 15 | 4.029% | 8.145% |
| 20 | 7.197% | 14.021% |
Relationships between endpoints
↥Index endpoint: N14_URETHRITISANDURSYNDR – Urethritis and urethral syndrome
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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