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Inflammatory disease of cervix uteri

DOID EFO Endpoint Browser PheWeb

N14_INFCERVIX

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N72
  • Hospital discharge: ICD-9 — 616
  • Hospital discharge: ICD-8 — 620
  • Cause of death: ICD-10 — N72
  • Cause of death: ICD-9 — 616
  • Cause of death: ICD-8 — 620

2 out of 7 registries used, show all original rules.

2267

4. Check minimum number of events

None

2267

5. Include endpoints

None

2267

6. Filter based on genotype QC (FinnGen only)

2195

Control definitions (FinnGen only)

Control exclude N14_FEMALEGENINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N70-N77
Name in latin Morbus inflammatorius cervicis uteri

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22447 22447 -
Only index persons 19473 19473 -
Unadjusted period prevalence (%)
Whole population 0.64 0.64 -
Only index persons 0.72 0.72 -
Median age at first event (years)
Whole population - 39.17 -
Only index persons - 37.35 -

-FinnGen-

Key figures

All Female Male
Number of individuals 2195 2195 -
Unadjusted period prevalence (%) 0.86 0.86 -
Median age at first event (years) 35.17 35.17 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint N14_INFCERVIX and mortality.

Females

Parameter HR [95% CI] p-value
N14_INFCERVIX 1.02 [0.88, 1.19] 0.795
Birth year 0.992 [0.98, 1.0] 0.062

During the follow-up period (1.1.1998 — 31.12.2019), 205 out of 4660 females with N14_INFCERVIX died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_INFCERVIX.

N-year risk Females Males
1 0.093% No data
5 0.52% No data
10 1.364% No data
15 2.594% No data
20 4.521% No data

Relationships between endpoints

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Index endpoint: N14_INFCERVIX – Inflammatory disease of cervix uteri

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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