No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
5377 |
4. Check minimum number of eventsNone |
5377 |
5. Include endpointsNone |
5377 |
6. Filter based on genotype QC (FinnGen only) |
5195 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
LSIL lesion of the cervix uteri, vagina or vulva
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 36492 | 36492 | - |
| Only index persons | 35540 | 35540 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.05 | 1.05 | - |
| Only index persons | 1.31 | 1.31 | - |
| Median age at first event (years) | |||
| Whole population | - | 35.02 | - |
| Only index persons | - | 34.91 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5195 | 5195 | - |
| Unadjusted period prevalence (%) | 2.04 | 2.04 | - |
| Median age at first event (years) | 36.07 | 36.07 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_FEMALE_GENITAL_LSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_FEMALE_GENITAL_LSIL | 1.019 [0.91, 1.15] | 0.75 |
| Birth year | 0.991 [0.98, 1.0] | 0.052 |
During the follow-up period (1.1.1998 — 31.12.2019), 1028 out of 27266 females with N14_FEMALE_GENITAL_LSIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_FEMALE_GENITAL_LSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.107% | No data |
| 5 | 0.611% | No data |
| 10 | 1.459% | No data |
| 15 | 2.814% | No data |
| 20 | 4.773% | No data |
Relationships between endpoints
↥Index endpoint: N14_FEMALE_GENITAL_LSIL – LSIL lesion of the cervix uteri, vagina or vulva
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data