Ovarian Endometriosis: A non-neoplastic disorder characterized by the growth of endometrial tissue in the ovaries. It results in the development of blood filled ovarian cysts (chocolate cysts), and creation of scars and adhesions.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
7377 |
4. Check minimum number of eventsNone |
7377 |
5. Include endpointsNone |
7377 |
6. Filter based on genotype QC (FinnGen only) |
7096 |
Control definitions (FinnGen only)
Control exclude
N14_FEMALEGENNONINF
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N80
Name in latin
Endometriosis ovarii
Similar endpoints
↥List of similar endpoints to
Endometriosis of ovary
based on the number of shared cases.
Similar with more cases:
- Endometriosis ASRM stages 3,4
- Endometriosis
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 54100 | 54100 | - |
| Only index persons | 51942 | 51942 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.55 | 1.55 | - |
| Only index persons | 1.91 | 1.91 | - |
| Median age at first event (years) | |||
| Whole population | - | 37.12 | - |
| Only index persons | - | 36.87 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7096 | 7096 | - |
| Unadjusted period prevalence (%) | 2.79 | 2.79 | - |
| Median age at first event (years) | 36.24 | 36.24 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_ENDOMETRIOSIS_OVARY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_ENDOMETRIOSIS_OVARY | 0.826 [0.72, 0.95] | 0.006 |
| Birth year | 0.99 [0.98, 1.0] | 0.025 |
During the follow-up period (1.1.1998 — 31.12.2019), 459 out of 24858 females with N14_ENDOMETRIOSIS_OVARY died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_ENDOMETRIOSIS_OVARY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.06% | No data |
| 5 | 0.467% | No data |
| 10 | 1.047% | No data |
| 15 | 1.983% | No data |
| 20 | 3.372% | No data |
Relationships between endpoints
↥Index endpoint: N14_ENDOMETRIOSIS_OVARY – Endometriosis of ovary
GWS hits: 30
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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