endometriosis: The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
18923 |
4. Check minimum number of eventsNone |
18923 |
5. Include endpoints |
18923 |
6. Filter based on genotype QC (FinnGen only) |
18260 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Endometriosis based on the number of shared cases.
Similar with more cases:
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 134008 | 134008 | - |
Only index persons | 127670 | 127670 | - |
Unadjusted period prevalence (%) | |||
Whole population | 3.84 | 3.84 | - |
Only index persons | 4.69 | 4.69 | - |
Median age at first event (years) | |||
Whole population | - | 38.33 | - |
Only index persons | - | 38.00 | - |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 18260 | 18260 | - |
Unadjusted period prevalence (%) | 7.17 | 7.17 | - |
Median age at first event (years) | 37.24 | 37.24 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_ENDOMETRIOSIS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
N14_ENDOMETRIOSIS | 0.751 [0.68, 0.84] | < 0.001 |
Birth year | 0.996 [0.99, 1.0] | 0.277 |
During the follow-up period (1.1.1998 — 31.12.2019), 1435 out of 55651 females with N14_ENDOMETRIOSIS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_ENDOMETRIOSIS.N-year risk | Females | Males |
---|---|---|
1 | 0.052% | No data |
5 | 0.428% | No data |
10 | 1.098% | No data |
15 | 2.202% | No data |
20 | 3.896% | No data |
Relationships between endpoints
↥Index endpoint: N14_ENDOMETRIOSIS – Endometriosis
GWS hits: 34