No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
5590 |
4. Check minimum number of eventsNone |
5590 |
5. Include endpointsNone |
5590 |
6. Filter based on genotype QC (FinnGen only) |
5385 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M65
Name in latin
Digitus contractus
Similar endpoints
↥List of similar endpoints to
Trigger finger
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 33598 | 21685 | 11813 |
| Only index persons | 32238 | 20993 | 11245 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.52 | 0.62 | 0.33 |
| Only index persons | 0.65 | 0.77 | 0.43 |
| Median age at first event (years) | |||
| Whole population | 55.40 | 55.88 | 54.55 |
| Only index persons | 55.63 | 56.01 | 54.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5385 | 3633 | 1752 |
| Unadjusted period prevalence (%) | 1.25 | 1.43 | 0.88 |
| Median age at first event (years) | 56.71 | 55.69 | 58.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_TRIGGERFINGER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_TRIGGERFINGER | 0.789 [0.71, 0.88] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.361 |
During the follow-up period (1.1.1998 — 31.12.2019), 1432 out of 18161 females with M13_TRIGGERFINGER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_TRIGGERFINGER | 0.711 [0.63, 0.8] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.042 |
During the follow-up period (1.1.1998 — 31.12.2019), 931 out of 9781 males with M13_TRIGGERFINGER died.
Mortality risk
Mortality risk for people of age
years, who have M13_TRIGGERFINGER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.08% | 0.144% |
| 5 | 0.428% | 0.79% |
| 10 | 1.125% | 2.099% |
| 15 | 2.259% | 4.267% |
| 20 | 3.922% | 7.412% |
Relationships between endpoints
↥Index endpoint: M13_TRIGGERFINGER – Trigger finger
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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