No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2943 |
4. Check minimum number of eventsNone |
2943 |
5. Include endpointsNone |
2943 |
6. Filter based on genotype QC (FinnGen only) |
2848 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M65-M68
Name in latin
Ruptura spontanea membranae synovialis sive tendinis
Similar endpoints
↥List of similar endpoints to
Spontaneous rupture of synovium and tendon
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 20336 | 10732 | 9533 |
| Only index persons | 19077 | 10245 | 8832 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.29 | 0.31 | 0.27 |
| Only index persons | 0.36 | 0.38 | 0.34 |
| Median age at first event (years) | |||
| Whole population | 57.06 | 60.51 | 53.09 |
| Only index persons | 56.66 | 60.14 | 52.61 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2848 | 1639 | 1209 |
| Unadjusted period prevalence (%) | 0.63 | 0.64 | 0.61 |
| Median age at first event (years) | 57.01 | 58.28 | 55.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_SPONTRUPTSYNOTEND and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPONTRUPTSYNOTEND | 1.04 [0.93, 1.17] | 0.499 |
| Birth year | 0.998 [0.99, 1.01] | 0.632 |
During the follow-up period (1.1.1998 — 31.12.2019), 1256 out of 7895 females with M13_SPONTRUPTSYNOTEND died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPONTRUPTSYNOTEND | 1.104 [0.98, 1.25] | 0.115 |
| Birth year | 0.986 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 997 out of 5873 males with M13_SPONTRUPTSYNOTEND died.
Mortality risk
Mortality risk for people of age
years, who have M13_SPONTRUPTSYNOTEND.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.08% | 0.222% |
| 5 | 0.608% | 1.195% |
| 10 | 1.552% | 3.132% |
| 15 | 3.037% | 5.739% |
| 20 | 5.617% | 9.955% |
Relationships between endpoints
↥Index endpoint: M13_SPONTRUPTSYNOTEND – Spontaneous rupture of synovium and tendon
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data