No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
899 |
4. Check minimum number of eventsNone |
899 |
5. Include endpointsNone |
899 |
6. Filter based on genotype QC (FinnGen only) |
863 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M67
Name in latin
Brevitas tendinis calcanei (Achillis) [acquisita]
Similar endpoints
↥List of similar endpoints to
Short Achilles tendon (acquired)
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7011 | 5002 | 1998 |
| Only index persons | 6948 | 4975 | 1973 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.14 | 0.06 |
| Only index persons | 0.15 | 0.18 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 54.21 | 56.04 | 49.69 |
| Only index persons | 54.39 | 56.10 | 50.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 863 | 658 | 205 |
| Unadjusted period prevalence (%) | 0.22 | 0.26 | 0.10 |
| Median age at first event (years) | 55.82 | 55.84 | 55.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_SHORTACHILLES and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SHORTACHILLES | 0.623 [0.5, 0.77] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.048 |
During the follow-up period (1.1.1998 — 31.12.2019), 124 out of 4439 females with M13_SHORTACHILLES died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SHORTACHILLES | 0.91 [0.7, 1.19] | 0.488 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 1773 males with M13_SHORTACHILLES died.
Mortality risk
Mortality risk for people of age
years, who have M13_SHORTACHILLES.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.049% | 0.151% |
| 5 | 0.323% | 0.933% |
| 10 | 0.926% | 2.262% |
| 15 | 1.691% | 4.5% |
| 20 | 2.845% | 7.592% |
Relationships between endpoints
↥Index endpoint: M13_SHORTACHILLES – Short Achilles tendon (acquired)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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