Prepatellar bursitis

M13_PREPATELLARBURSITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M70.4
  • Hospital discharge: ICD-9 7266E
  • Cause of death: ICD-10 M70.4
  • Cause of death: ICD-9 7266E

2 out of 7 registries used, show all original rules.

1595

4. Check minimum number of events

None

1595

5. Include endpoints

None

1595

6. Filter based on genotype QC (FinnGen only)

1537

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M70
Name in latin Bursitis praepatellaris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14453 3093 11319
Only index persons 13663 2899 10764
Unadjusted period prevalence (%)
Whole population 0.27 0.09 0.32
Only index persons 0.35 0.11 0.41
Median age at first event (years)
Whole population 47.35 50.33 46.53
Only index persons 46.91 49.76 46.14

-FinnGen-

Key figures

All Female Male
Number of individuals 1537 378 1159
Unadjusted period prevalence (%) 0.48 0.15 0.58
Median age at first event (years) 49.97 49.46 50.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint M13_PREPATELLARBURSITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_PREPATELLARBURSITIS 1.417 [1.2, 1.67] < 0.001
Birth year 0.994 [0.99, 1.0] 0.164

During the follow-up period (1.1.1998 — 31.12.2019), 323 out of 2303 females with M13_PREPATELLARBURSITIS died.

Males

Parameter HR [95% CI] p-value
M13_PREPATELLARBURSITIS 1.054 [0.94, 1.18] 0.365
Birth year 0.99 [0.98, 1.0] 0.034

During the follow-up period (1.1.1998 — 31.12.2019), 921 out of 8245 males with M13_PREPATELLARBURSITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_PREPATELLARBURSITIS.

N-year risk Females Males
1 0.13% 0.235%
5 0.702% 1.398%
10 1.837% 3.504%
15 3.515% 6.746%
20 6.225% 11.358%

Relationships between endpoints

Index endpoint: M13_PREPATELLARBURSITIS – Prepatellar bursitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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