No definition available.
Other/unspecified soft tissue disorders related to use, overuse and pressure
EFO MESH Endpoint Browser PheWeb
M13_OVERUSENAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1019 |
4. Check minimum number of eventsNone |
1019 |
5. Include endpointsNone |
1019 |
6. Filter based on genotype QC (FinnGen only) |
987 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other/unspecified soft tissue disorders related to use, overuse and pressure
based on the number of shared cases.
Similar with more cases:
- Soft tissue disorders related to use, overuse and pressure
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7457 | 4293 | 3132 |
| Only index persons | 7151 | 4134 | 3017 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.09 |
| Only index persons | 0.14 | 0.15 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 44.30 | 46.78 | 40.94 |
| Only index persons | 43.99 | 46.43 | 40.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 987 | 670 | 317 |
| Unadjusted period prevalence (%) | 0.23 | 0.26 | 0.16 |
| Median age at first event (years) | 50.95 | 50.21 | 52.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_OVERUSENAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_OVERUSENAS | 1.099 [0.95, 1.27] | 0.192 |
| Birth year | 1.001 [0.99, 1.01] | 0.813 |
During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 3326 females with M13_OVERUSENAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_OVERUSENAS | 1.009 [0.86, 1.19] | 0.91 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 216 out of 2232 males with M13_OVERUSENAS died.
Mortality risk
Mortality risk for people of age
years, who have M13_OVERUSENAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.119% | 0.23% |
| 5 | 0.688% | 1.344% |
| 10 | 1.744% | 3.272% |
| 15 | 3.526% | 6.085% |
| 20 | 6.667% | 10.218% |
Relationships between endpoints
↥Index endpoint: M13_OVERUSENAS – Other/unspecified soft tissue disorders related to use, overuse and pressure
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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