No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
96 |
4. Check minimum number of eventsNone |
96 |
5. Include endpointsNone |
96 |
6. Filter based on genotype QC (FinnGen only) |
94 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Myositis ossificans
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 910 | 446 | 457 |
| Only index persons | 779 | 393 | 386 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 56.97 | 59.89 | 54.01 |
| Only index persons | 54.29 | 56.07 | 52.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 94 | 44 | 50 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 51.58 | 49.51 | 53.40 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_MYOSITISOSSIF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MYOSITISOSSIF | 1.458 [1.13, 1.89] | 0.004 |
| Birth year | 0.992 [0.98, 1.0] | 0.071 |
During the follow-up period (1.1.1998 — 31.12.2019), 114 out of 381 females with M13_MYOSITISOSSIF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MYOSITISOSSIF | 1.557 [1.22, 1.98] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.048 |
During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 355 males with M13_MYOSITISOSSIF died.
Mortality risk
Mortality risk for people of age
years, who have M13_MYOSITISOSSIF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.146% | 0.386% |
| 5 | 0.821% | 2.098% |
| 10 | 1.829% | 5.174% |
| 15 | 3.638% | 9.824% |
| 20 | 6.346% | 16.21% |
Relationships between endpoints
↥Index endpoint: M13_MYOSITISOSSIF – Myositis ossificans
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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