No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
9444 |
4. Check minimum number of eventsNone |
9444 |
5. Include endpointsNone |
9444 |
6. Filter based on genotype QC (FinnGen only) |
9085 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M67
Name in latin
Ganglion
Similar endpoints
↥List of similar endpoints to
Ganglion
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 69629 | 44954 | 24427 |
| Only index persons | 67251 | 43826 | 23425 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.07 | 1.29 | 0.68 |
| Only index persons | 1.36 | 1.61 | 0.89 |
| Median age at first event (years) | |||
| Whole population | 42.92 | 43.29 | 42.27 |
| Only index persons | 42.75 | 43.15 | 41.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9085 | 6515 | 2570 |
| Unadjusted period prevalence (%) | 2.20 | 2.56 | 1.29 |
| Median age at first event (years) | 45.98 | 44.64 | 49.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_GANGLION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_GANGLION | 0.786 [0.71, 0.87] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.649 |
During the follow-up period (1.1.1998 — 31.12.2019), 1758 out of 33603 females with M13_GANGLION died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_GANGLION | 0.775 [0.7, 0.86] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 1423 out of 18421 males with M13_GANGLION died.
Mortality risk
Mortality risk for people of age
years, who have M13_GANGLION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.12% |
| 5 | 0.544% | 0.753% |
| 10 | 1.218% | 1.903% |
| 15 | 2.473% | 3.892% |
| 20 | 4.444% | 6.459% |
Relationships between endpoints
↥Index endpoint: M13_GANGLION – Ganglion
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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