No definition available.
Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies
EFO MESH Endpoint Browser PheWeb
M13_DISSYNOTENDNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1771 |
4. Check minimum number of eventsNone |
1771 |
5. Include endpointsNone |
1771 |
6. Filter based on genotype QC (FinnGen only) |
1714 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14816 | 7673 | 7115 |
| Only index persons | 14399 | 7513 | 6886 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.21 | 0.22 | 0.20 |
| Only index persons | 0.27 | 0.28 | 0.26 |
| Median age at first event (years) | |||
| Whole population | 40.04 | 41.07 | 38.92 |
| Only index persons | 39.82 | 40.87 | 38.67 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1714 | 1090 | 624 |
| Unadjusted period prevalence (%) | 0.39 | 0.43 | 0.31 |
| Median age at first event (years) | 45.22 | 44.68 | 46.17 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_DISSYNOTENDNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DISSYNOTENDNAS | 0.733 [0.63, 0.85] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.844 |
During the follow-up period (1.1.1998 — 31.12.2019), 236 out of 6104 females with M13_DISSYNOTENDNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DISSYNOTENDNAS | 0.771 [0.68, 0.88] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.036 |
During the follow-up period (1.1.1998 — 31.12.2019), 331 out of 5726 males with M13_DISSYNOTENDNAS died.
Mortality risk
Mortality risk for people of age
years, who have M13_DISSYNOTENDNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | 0.162% |
| 5 | 0.457% | 0.952% |
| 10 | 1.157% | 2.383% |
| 15 | 2.229% | 4.534% |
| 20 | 4.169% | 8.02% |
Relationships between endpoints
↥Index endpoint: M13_DISSYNOTENDNAS – Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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