No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
237 |
4. Check minimum number of eventsNone |
237 |
5. Include endpointsNone |
237 |
6. Filter based on genotype QC (FinnGen only) |
225 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M62
Name in latin
Diastasis musculi
Similar endpoints
↥List of similar endpoints to
Diastasis of muscle
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1432 | 834 | 588 |
| Only index persons | 1376 | 813 | 563 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.12 | 41.83 | 57.15 |
| Only index persons | 48.03 | 41.56 | 57.37 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 225 | 146 | 79 |
| Unadjusted period prevalence (%) | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | 49.87 | 43.41 | 61.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_DIASTASIS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DIASTASIS | 0.982 [0.75, 1.28] | 0.891 |
| Birth year | 0.99 [0.98, 1.0] | 0.051 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 493 males with M13_DIASTASIS died.
Mortality risk
Mortality risk for people of age
years, who have M13_DIASTASIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.197% |
| 5 | No data | 1.252% |
| 10 | No data | 3.111% |
| 15 | No data | 5.867% |
| 20 | No data | 10.226% |
Relationships between endpoints
↥Index endpoint: M13_DIASTASIS – Diastasis of muscle
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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