No definition available.
Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist
EFO MESH Endpoint Browser PheWeb
M13_CHRONSYNOVITISHANDWRIST
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
484 |
4. Check minimum number of eventsNone |
484 |
5. Include endpointsNone |
484 |
6. Filter based on genotype QC (FinnGen only) |
462 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist
based on the number of shared cases.
Similar with more cases:
- Soft tissue disorders related to use, overuse and pressure
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3653 | 2118 | 1522 |
| Only index persons | 3478 | 2036 | 1442 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.07 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 51.39 | 52.07 | 50.41 |
| Only index persons | 50.83 | 51.70 | 49.59 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 462 | 306 | 156 |
| Unadjusted period prevalence (%) | 0.11 | 0.12 | 0.08 |
| Median age at first event (years) | 51.28 | 50.63 | 52.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_CHRONSYNOVITISHANDWRIST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CHRONSYNOVITISHANDWRIST | 1.108 [0.94, 1.3] | 0.21 |
| Birth year | 0.995 [0.99, 1.0] | 0.231 |
During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 1878 females with M13_CHRONSYNOVITISHANDWRIST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CHRONSYNOVITISHANDWRIST | 1.158 [0.99, 1.36] | 0.074 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 238 out of 1368 males with M13_CHRONSYNOVITISHANDWRIST died.
Mortality risk
Mortality risk for people of age
years, who have M13_CHRONSYNOVITISHANDWRIST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.258% |
| 5 | 0.652% | 1.328% |
| 10 | 1.581% | 3.134% |
| 15 | 2.973% | 5.697% |
| 20 | 5.195% | 10.039% |
Relationships between endpoints
↥Index endpoint: M13_CHRONSYNOVITISHANDWRIST – Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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