Calcific tendinitis

M13_CALCTENDINITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M65.2
  • Cause of death: ICD-10 M65.2

2 out of 7 registries used, show all original rules.

307

4. Check minimum number of events

None

307

5. Include endpoints

None

307

6. Filter based on genotype QC (FinnGen only)

298

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M65
Name in latin Tendinitis calcificans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2142 1286 852
Only index persons 2086 1262 824
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.02
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 50.24 50.75 49.52
Only index persons 50.18 50.65 49.47

-FinnGen-

Key figures

All Female Male
Number of individuals 298 183 115
Unadjusted period prevalence (%) 0.07 0.07 0.06
Median age at first event (years) 52.53 50.31 56.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint M13_CALCTENDINITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.851 [0.67, 1.07] 0.175
Birth year 0.995 [0.99, 1.0] 0.238

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 1127 females with M13_CALCTENDINITIS died.

Males

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.862 [0.68, 1.09] 0.209
Birth year 0.988 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 721 males with M13_CALCTENDINITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_CALCTENDINITIS.

N-year risk Females Males
1 0.077% 0.162%
5 0.494% 0.958%
10 1.316% 2.609%
15 2.429% 4.989%
20 4.252% 8.412%

Relationships between endpoints

Index endpoint: M13_CALCTENDINITIS – Calcific tendinitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data