No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
82 |
4. Check minimum number of eventsNone |
82 |
5. Include endpointsNone |
82 |
6. Filter based on genotype QC (FinnGen only) |
80 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M60-M63
Name in latin
Calcificatio et ossificatio musculi
Similar endpoints
↥List of similar endpoints to
Calcification and ossification of muscle
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 594 | 264 | 323 |
| Only index persons | 508 | 233 | 275 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 53.41 | 53.62 | 53.09 |
| Only index persons | 52.03 | 52.67 | 51.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 80 | 35 | 45 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 52.22 | 46.80 | 56.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_CALCIOSSIMUSCLE and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CALCIOSSIMUSCLE | 1.461 [1.02, 2.09] | 0.037 |
| Birth year | 0.993 [0.98, 1.0] | 0.108 |
During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 217 males with M13_CALCIOSSIMUSCLE died.
Mortality risk
Mortality risk for people of age
years, who have M13_CALCIOSSIMUSCLE.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.288% |
| 5 | No data | 2.012% |
| 10 | No data | 5.072% |
| 15 | No data | 9.751% |
| 20 | No data | 16.361% |
Relationships between endpoints
↥Index endpoint: M13_CALCIOSSIMUSCLE – Calcification and ossification of muscle
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data