Other bursitis of knee

M13_BURSITISKNEEOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M70.5
  • Hospital discharge: ICD-9 7266B|7266C|7266X
  • Cause of death: ICD-10 M70.5
  • Cause of death: ICD-9 7266B|7266C|7266X

2 out of 7 registries used, show all original rules.

445

4. Check minimum number of events

None

445

5. Include endpoints

None

445

6. Filter based on genotype QC (FinnGen only)

432

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M70
Name in latin Alia bursitis genus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3713 1232 2461
Only index persons 3540 1170 2370
Unadjusted period prevalence (%)
Whole population 0.06 0.04 0.07
Only index persons 0.07 0.04 0.09
Median age at first event (years)
Whole population 46.67 49.87 45.16
Only index persons 46.57 49.25 45.25

-FinnGen-

Key figures

All Female Male
Number of individuals 432 162 270
Unadjusted period prevalence (%) 0.11 0.06 0.14
Median age at first event (years) 50.68 50.72 50.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint M13_BURSITISKNEEOTH and mortality.

Females

Parameter HR [95% CI] p-value
M13_BURSITISKNEEOTH 1.189 [0.9, 1.56] 0.215
Birth year 0.992 [0.98, 1.0] 0.077

During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 858 females with M13_BURSITISKNEEOTH died.

Males

Parameter HR [95% CI] p-value
M13_BURSITISKNEEOTH 1.013 [0.83, 1.24] 0.9
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 145 out of 1693 males with M13_BURSITISKNEEOTH died.

Mortality risk

Mortality risk for people of age

years, who have M13_BURSITISKNEEOTH.

N-year risk Females Males
1 0.081% 0.2%
5 0.569% 1.203%
10 1.57% 2.944%
15 2.927% 5.658%
20 5.204% 9.468%

Relationships between endpoints

Index endpoint: M13_BURSITISKNEEOTH – Other bursitis of knee

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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