synovitis: ['Inflammation of the SYNOVIAL MEMBRANE [ MeSH ]']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
188 |
4. Check minimum number of eventsNone |
188 |
5. Include endpointsNone |
188 |
6. Filter based on genotype QC (FinnGen only) |
180 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M65
Name in latin
Abscessus vaginae tendinis
Similar endpoints
↥List of similar endpoints to
Abscess of tendon sheath
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1425 | 675 | 749 |
| Only index persons | 1365 | 650 | 715 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 48.93 | 51.37 | 46.74 |
| Only index persons | 48.50 | 51.08 | 46.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 180 | 104 | 76 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 52.64 | 49.82 | 56.49 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_ABSCTENDON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ABSCTENDON | 1.179 [0.9, 1.55] | 0.235 |
| Birth year | 0.999 [0.99, 1.01] | 0.723 |
During the follow-up period (1.1.1998 — 31.12.2019), 76 out of 589 females with M13_ABSCTENDON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ABSCTENDON | 1.623 [1.22, 2.17] | 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 82 out of 624 males with M13_ABSCTENDON died.
Mortality risk
Mortality risk for people of age
years, who have M13_ABSCTENDON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.108% | 0.294% |
| 5 | 0.704% | 1.659% |
| 10 | 1.838% | 4.204% |
| 15 | 3.309% | 8.465% |
| 20 | 6.222% | 14.247% |
Relationships between endpoints
↥Index endpoint: M13_ABSCTENDON – Abscess of tendon sheath
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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