No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3555 |
4. Check minimum number of eventsNone |
3555 |
5. Include endpointsNone |
3555 |
6. Filter based on genotype QC (FinnGen only) |
3407 |
Control definitions (FinnGen only)
Control exclude
L12_INFECT_SKIN
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L00-L08
Name in latin
Cysta pilonidalis
Similar endpoints
↥List of similar endpoints to
Pilonidal cyst
based on the number of shared cases.
Similar with more cases:
- Infections of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 37426 | 10491 | 26770 |
| Only index persons | 36039 | 10189 | 25850 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.62 | 0.30 | 0.75 |
| Only index persons | 0.81 | 0.37 | 0.99 |
| Median age at first event (years) | |||
| Whole population | 26.92 | 24.70 | 27.76 |
| Only index persons | 26.75 | 24.65 | 27.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3407 | 1300 | 2107 |
| Unadjusted period prevalence (%) | 0.85 | 0.51 | 1.06 |
| Median age at first event (years) | 29.18 | 26.11 | 31.08 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_PILONIDALCYST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PILONIDALCYST | 1.434 [1.18, 1.74] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 162 out of 6711 females with L12_PILONIDALCYST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PILONIDALCYST | 1.341 [1.19, 1.51] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 792 out of 18376 males with L12_PILONIDALCYST died.
Mortality risk
Mortality risk for people of age
years, who have L12_PILONIDALCYST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.127% | 0.249% |
| 5 | 0.809% | 1.604% |
| 10 | 1.803% | 3.91% |
| 15 | 3.667% | 7.756% |
| 20 | 5.968% | 12.828% |
Relationships between endpoints
↥Index endpoint: L12_PILONIDALCYST – Pilonidal cyst
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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