No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2288 |
4. Check minimum number of eventsNone |
2288 |
5. Include endpointsNone |
2288 |
6. Filter based on genotype QC (FinnGen only) |
2206 |
Control definitions (FinnGen only)
Control exclude
L12_INFECT_SKIN
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L00-L08
Name in latin
Lymphadenitis acuta
Similar endpoints
↥List of similar endpoints to
Acute lymphadenitis
based on the number of shared cases.
Similar with more cases:
- Infections of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 27936 | 12727 | 15117 |
| Only index persons | 24318 | 11304 | 13014 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.39 | 0.36 | 0.42 |
| Only index persons | 0.46 | 0.42 | 0.50 |
| Median age at first event (years) | |||
| Whole population | 18.02 | 22.26 | 14.28 |
| Only index persons | 18.72 | 22.85 | 15.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2206 | 1299 | 907 |
| Unadjusted period prevalence (%) | 0.49 | 0.51 | 0.46 |
| Median age at first event (years) | 28.86 | 29.38 | 28.12 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_LYMPHADENITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_LYMPHADENITIS | 1.573 [1.39, 1.78] | < 0.001 |
| Birth year | 1.0 [0.99, 1.01] | 0.956 |
During the follow-up period (1.1.1998 — 31.12.2019), 671 out of 8609 females with L12_LYMPHADENITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_LYMPHADENITIS | 1.915 [1.68, 2.19] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 847 out of 9296 males with L12_LYMPHADENITIS died.
Mortality risk
Mortality risk for people of age
years, who have L12_LYMPHADENITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.179% | 0.322% |
| 5 | 1.175% | 1.864% |
| 10 | 2.562% | 4.926% |
| 15 | 5.328% | 9.104% |
| 20 | 9.277% | 15.178% |
Relationships between endpoints
↥Index endpoint: L12_LYMPHADENITIS – Acute lymphadenitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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