No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
111 |
4. Check minimum number of eventsNone |
111 |
5. Include endpointsNone |
111 |
6. Filter based on genotype QC (FinnGen only) |
103 |
Control definitions (FinnGen only)
Control exclude
L12_OTHERSKINSUBCUTIS
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L95
Name in latin
Vasculitis lividoides
Similar endpoints
↥List of similar endpoints to
Livedoid vasculitis
based on the number of shared cases.
Similar with more cases:
- Vasculitis limited to skin, not elsewhere classified
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 736 | 442 | 289 |
| Only index persons | 645 | 394 | 251 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 62.30 | 64.34 | 59.28 |
| Only index persons | 60.70 | 62.60 | 57.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 103 | 62 | 41 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 62.59 | 63.98 | 60.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_LIVEDOIDVASC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_LIVEDOIDVASC | 2.31 [1.71, 3.12] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.057 |
During the follow-up period (1.1.1998 — 31.12.2019), 135 out of 387 females with L12_LIVEDOIDVASC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_LIVEDOIDVASC | 2.531 [1.81, 3.53] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.037 |
During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 258 males with L12_LIVEDOIDVASC died.
Mortality risk
Mortality risk for people of age
years, who have L12_LIVEDOIDVASC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.23% | 0.457% |
| 5 | 1.255% | 2.884% |
| 10 | 3.34% | 7.557% |
| 15 | 5.871% | 13.411% |
| 20 | 10.136% | 22.15% |
Relationships between endpoints
↥Index endpoint: L12_LIVEDOIDVASC – Livedoid vasculitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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