No definition available.
Other and unspecified hypertrophic disorders of skin
L12_HYPERTROPHICNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
200 |
4. Check minimum number of eventsNone |
200 |
5. Include endpointsNone |
200 |
6. Filter based on genotype QC (FinnGen only) |
185 |
Control definitions (FinnGen only)
Control exclude
L12_OTHERSKINSUBCUTIS
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified hypertrophic disorders of skin
based on the number of shared cases.
Similar with more cases:
- Hypertrophic disorders of skin
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1556 | 1015 | 529 |
| Only index persons | 1482 | 982 | 500 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.01 |
| Only index persons | 0.03 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 42.51 | 42.48 | 42.83 |
| Only index persons | 42.62 | 42.36 | 43.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 185 | 131 | 54 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | 49.09 | 46.08 | 56.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_HYPERTROPHICNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_HYPERTROPHICNAS | 1.269 [0.91, 1.77] | 0.16 |
| Birth year | 0.991 [0.98, 1.0] | 0.048 |
During the follow-up period (1.1.1998 — 31.12.2019), 57 out of 816 females with L12_HYPERTROPHICNAS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_HYPERTROPHICNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.101% | No data |
| 5 | 0.661% | No data |
| 10 | 1.736% | No data |
| 15 | 3.21% | No data |
| 20 | 5.77% | No data |
Relationships between endpoints
↥Index endpoint: L12_HYPERTROPHICNAS – Other and unspecified hypertrophic disorders of skin
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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