iritis: Inflammation of the iris.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
649 |
4. Check minimum number of eventsNone |
649 |
5. Include endpointsNone |
649 |
6. Filter based on genotype QC (FinnGen only) |
591 |
Control definitions (FinnGen only)
Control exclude
L12_DISORDSKINAPPENDIX
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
L68
Name in latin
Hirsutismus
Similar endpoints
↥List of similar endpoints to
Hirsutism in women
based on the number of shared cases.
Similar with more cases:
- Hypertrichosis
- Disorders of skin appendages
- Polycystic ovarian syndrome, consortium definition
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4246 | 4246 | - |
| Only index persons | 4165 | 4165 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.12 | - |
| Only index persons | 0.15 | 0.15 | - |
| Median age at first event (years) | |||
| Whole population | - | 30.89 | - |
| Only index persons | - | 30.87 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 591 | 591 | - |
| Unadjusted period prevalence (%) | 0.23 | 0.23 | - |
| Median age at first event (years) | 33.44 | 33.44 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_HIRSUTISM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_HIRSUTISM | 1.3 [1.05, 1.61] | 0.015 |
| Birth year | 0.998 [0.99, 1.01] | 0.583 |
During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 3551 females with L12_HIRSUTISM died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_HIRSUTISM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | No data |
| 5 | 0.784% | No data |
| 10 | 2.05% | No data |
| 15 | 4.113% | No data |
| 20 | 7.223% | No data |
Relationships between endpoints
↥Index endpoint: L12_HIRSUTISM – Hirsutism in women
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data