obsolete_alopecia:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
199 |
4. Check minimum number of eventsNone |
199 |
5. Include endpoints |
233 |
6. Filter based on genotype QC (FinnGen only) |
228 |
Control definitions (FinnGen only)
Control exclude
L12_DISORDSKINAPPENDIX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Alopecia cicatrisans
Similar endpoints
↥List of similar endpoints to
Cicatricial alopecia [scarring hair loss]
based on the number of shared cases.
Similar with more cases:
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1938 | 1201 | 729 |
| Only index persons | 1789 | 1155 | 634 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.69 | 56.69 | 35.57 |
| Only index persons | 48.37 | 56.89 | 32.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 228 | 171 | 57 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.03 |
| Median age at first event (years) | 54.42 | 57.94 | 43.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_HAIRLOSSSCAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_HAIRLOSSSCAR | 1.016 [0.78, 1.33] | 0.91 |
| Birth year | 0.996 [0.99, 1.0] | 0.377 |
During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 867 females with L12_HAIRLOSSSCAR died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_HAIRLOSSSCAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | No data |
| 5 | 0.624% | No data |
| 10 | 1.506% | No data |
| 15 | 3.054% | No data |
| 20 | 5.469% | No data |
Relationships between endpoints
↥Index endpoint: L12_HAIRLOSSSCAR – Cicatricial alopecia [scarring hair loss]
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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