Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.
Follicular cysts of skin and subcutaneous tissue
DOID EFO Endpoint Browser PheWeb
L12_FOLLICULARCYST
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
7099 |
4. Check minimum number of eventsNone |
7099 |
5. Include endpointsNone |
7099 |
6. Filter based on genotype QC (FinnGen only) |
6832 |
Control definitions (FinnGen only)
Control exclude
L12_DISORDSKINAPPENDIX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Cystae folliculares cutis et telae subcutaneae
Similar endpoints
↥List of similar endpoints to
Follicular cysts of skin and subcutaneous tissue
based on the number of shared cases.
Similar with more cases:
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 61481 | 27084 | 34069 |
| Only index persons | 57768 | 25810 | 31958 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.87 | 0.78 | 0.95 |
| Only index persons | 1.10 | 0.95 | 1.22 |
| Median age at first event (years) | |||
| Whole population | 46.97 | 49.97 | 44.59 |
| Only index persons | 46.94 | 50.14 | 44.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6832 | 3476 | 3356 |
| Unadjusted period prevalence (%) | 1.52 | 1.37 | 1.69 |
| Median age at first event (years) | 52.69 | 51.42 | 54.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_FOLLICULARCYST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FOLLICULARCYST | 1.164 [1.05, 1.29] | 0.005 |
| Birth year | 0.995 [0.99, 1.0] | 0.199 |
During the follow-up period (1.1.1998 — 31.12.2019), 2238 out of 21848 females with L12_FOLLICULARCYST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FOLLICULARCYST | 1.276 [1.15, 1.41] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 3461 out of 27016 males with L12_FOLLICULARCYST died.
Mortality risk
Mortality risk for people of age
years, who have L12_FOLLICULARCYST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.214% |
| 5 | 0.639% | 1.33% |
| 10 | 1.63% | 3.333% |
| 15 | 3.187% | 6.424% |
| 20 | 5.821% | 10.684% |
Relationships between endpoints
↥Index endpoint: L12_FOLLICULARCYST – Follicular cysts of skin and subcutaneous tissue
GWS hits: 7
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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