photosensitivity disease: Photosensitivity refers to various symptoms, diseases and conditions caused or aggravated by exposure to sunlight.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
233 |
4. Check minimum number of eventsNone |
233 |
5. Include endpointsNone |
233 |
6. Filter based on genotype QC (FinnGen only) |
225 |
Control definitions (FinnGen only)
Control exclude
L12_RADIATIONRELATEDSKIN
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L57
Name in latin
Cutis laxa senilis
Similar endpoints
↥List of similar endpoints to
Cutis laxa senilis
based on the number of shared cases.
Similar with more cases:
- Skin changes due to chronic exposure to nonionizing radiation
- Radiation-related disorders of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1483 | 1319 | 155 |
| Only index persons | 1385 | 1244 | 141 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.00 |
| Only index persons | 0.04 | 0.05 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 55.73 | 54.96 | 62.05 |
| Only index persons | 55.47 | 54.72 | 62.05 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 225 | 209 | 16 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.01 |
| Median age at first event (years) | 55.09 | 54.48 | 63.03 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_CUTLAXSEN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_CUTLAXSEN | 0.901 [0.73, 1.12] | 0.345 |
| Birth year | 0.992 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 879 females with L12_CUTLAXSEN died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_CUTLAXSEN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.068% | No data |
| 5 | 0.471% | No data |
| 10 | 1.246% | No data |
| 15 | 2.254% | No data |
| 20 | 3.936% | No data |
Relationships between endpoints
↥Index endpoint: L12_CUTLAXSEN – Cutis laxa senilis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data