cellulitis: Inflammation of the dermis and subcutaneous tissues caused by a bacterial infection. Symptoms include erythema, edema, and pain to the affected area.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
8766 |
4. Check minimum number of eventsNone |
8766 |
5. Include endpointsNone |
8766 |
6. Filter based on genotype QC (FinnGen only) |
8429 |
Control definitions (FinnGen only)
Control exclude
L12_INFECT_SKIN
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L00-L08
Name in latin
Cellulitis
Similar endpoints
↥List of similar endpoints to
Cellulitis
based on the number of shared cases.
Similar with more cases:
- Infections of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 86474 | 36556 | 49337 |
| Only index persons | 74556 | 31741 | 42815 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.23 | 1.05 | 1.38 |
| Only index persons | 1.44 | 1.17 | 1.63 |
| Median age at first event (years) | |||
| Whole population | 45.08 | 49.87 | 41.44 |
| Only index persons | 44.93 | 49.74 | 41.36 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8429 | 3963 | 4466 |
| Unadjusted period prevalence (%) | 1.92 | 1.56 | 2.24 |
| Median age at first event (years) | 53.06 | 51.90 | 54.09 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_CELLULITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_CELLULITIS | 2.424 [2.14, 2.74] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.136 |
During the follow-up period (1.1.1998 — 31.12.2019), 4994 out of 25495 females with L12_CELLULITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_CELLULITIS | 2.541 [2.25, 2.87] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 6394 out of 32414 males with L12_CELLULITIS died.
Mortality risk
Mortality risk for people of age
years, who have L12_CELLULITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.181% | 0.48% |
| 5 | 1.446% | 2.899% |
| 10 | 3.584% | 7.607% |
| 15 | 6.247% | 13.708% |
| 20 | 10.945% | 22.427% |
Relationships between endpoints
↥Index endpoint: L12_CELLULITIS – Cellulitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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