androgenetic alopecia:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
260 |
4. Check minimum number of eventsNone |
260 |
5. Include endpointsNone |
260 |
6. Filter based on genotype QC (FinnGen only) |
247 |
Control definitions (FinnGen only)
Control exclude
L12_DISORDSKINAPPENDIX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Alopecia androgenica
Similar endpoints
↥List of similar endpoints to
Androgenic alopecia
based on the number of shared cases.
Similar with more cases:
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1684 | 1684 | - |
| Only index persons | 1625 | 1625 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | - |
| Only index persons | 0.06 | 0.06 | - |
| Median age at first event (years) | |||
| Whole population | - | 43.96 | - |
| Only index persons | - | 43.20 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 247 | 247 | - |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | - |
| Median age at first event (years) | 50.20 | 50.20 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_ALOPECANDRO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ALOPECANDRO | 1.266 [1.01, 1.59] | 0.043 |
| Birth year | 0.997 [0.99, 1.01] | 0.532 |
During the follow-up period (1.1.1998 — 31.12.2019), 92 out of 1383 females with L12_ALOPECANDRO died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_ALOPECANDRO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.143% | No data |
| 5 | 0.796% | No data |
| 10 | 1.985% | No data |
| 15 | 3.694% | No data |
| 20 | 6.598% | No data |
Relationships between endpoints
↥Index endpoint: L12_ALOPECANDRO – Androgenic alopecia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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