No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
KRA_PSY_ANYMENTAL
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F90-F98
Name in latin
Perturbationes modi se gerendi et emotionales mixtae
Similar endpoints
↥List of similar endpoints to
Mixed disorders of conduct and emotions
based on the number of shared cases.
Similar with more cases:
- Mixed disorders of conduct and emotions
- Mixed disorders of conduct and emotions
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 27425 | 8978 | 18414 |
| Only index persons | 25161 | 8414 | 16747 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.43 | 0.26 | 0.51 |
| Only index persons | 0.53 | 0.31 | 0.64 |
| Median age at first event (years) | |||
| Whole population | 11.83 | 14.01 | 10.77 |
| Only index persons | 12.12 | 14.16 | 11.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 851 | 491 | 360 |
| Unadjusted period prevalence (%) | 0.19 | 0.19 | 0.18 |
| Median age at first event (years) | 14.06 | 15.05 | 12.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint KRA_PSY_CODUCTEMOT_EXMORE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| KRA_PSY_CODUCTEMOT_EXMORE | 5.297 [3.83, 7.32] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.143 |
During the follow-up period (1.1.1998 — 31.12.2019), 162 out of 8101 females with KRA_PSY_CODUCTEMOT_EXMORE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| KRA_PSY_CODUCTEMOT_EXMORE | 4.347 [3.66, 5.17] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 313 out of 16552 males with KRA_PSY_CODUCTEMOT_EXMORE died.
Mortality risk
Mortality risk for people of age
years, who have KRA_PSY_CODUCTEMOT_EXMORE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.412% | 0.989% |
| 5 | 2.258% | 5.119% |
| 10 | 6.302% | 11.697% |
| 15 | 12.436% | 22.129% |
| 20 | 22.163% | 34.888% |
Relationships between endpoints
↥Index endpoint: KRA_PSY_CODUCTEMOT_EXMORE – Mixed disorders of conduct and emotions
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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