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Disease of hard tissues of teeth, NOS

Endpoint Browser PheWeb

K11_TEETH_HARD_NOS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K03.80, K03.81, K03.88, K03.9
  • Hospital discharge: ICD-9 — 521[8-9]
  • Hospital discharge: ICD-8 — 521[8-9]
  • Cause of death: ICD-10 — K03.80, K03.81, K03.88, K03.9
  • Cause of death: ICD-9 — 521[8-9]
  • Cause of death: ICD-8 — 521[8-9]

2 out of 7 registries used, show all original rules.

240

4. Check minimum number of events

None

240

5. Include endpoints

None

240

6. Filter based on genotype QC (FinnGen only)

230

Control definitions (FinnGen only)

Control exclude K11_ORAL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1080 609 461
Only index persons 999 573 426
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 45.31 46.73 43.69
Only index persons 44.53 45.88 42.72

-FinnGen-

Key figures

All Female Male
Number of individuals 230 139 91
Unadjusted period prevalence (%) 0.05 0.05 0.05
Median age at first event (years) 55.93 56.92 54.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

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Association

Association between endpoint K11_TEETH_HARD_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_TEETH_HARD_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

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Index endpoint: K11_TEETH_HARD_NOS – Disease of hard tissues of teeth, NOS

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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