dumping syndrome: Gastrointestinal symptoms resulting from an absent or nonfunctioning pylorus.
Postprocedural disorders of digestive system, not elsewhere classified
DOID EFO Endpoint Browser PheWeb
K11_POSTOPDIS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1042 |
4. Check minimum number of eventsNone |
1042 |
5. Include endpointsNone |
1042 |
6. Filter based on genotype QC (FinnGen only) |
1002 |
Control definitions (FinnGen only)
Control exclude
K11_OTHDIG
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K90-K93
Name in latin
Morbositates systematis digestorii post interventiones non alibi classificatae
Similar endpoints
↥List of similar endpoints to
Postprocedural disorders of digestive system, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Other diseases of the digestive system
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7197 | 3826 | 3286 |
| Only index persons | 5769 | 3168 | 2601 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.09 |
| Only index persons | 0.11 | 0.12 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 63.63 | 63.76 | 63.30 |
| Only index persons | 61.79 | 61.73 | 61.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1002 | 555 | 447 |
| Unadjusted period prevalence (%) | 0.22 | 0.22 | 0.22 |
| Median age at first event (years) | 59.00 | 55.00 | 63.96 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_POSTOPDIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_POSTOPDIS | 2.113 [1.84, 2.42] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 1050 out of 2932 females with K11_POSTOPDIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_POSTOPDIS | 2.286 [1.97, 2.65] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1123 out of 2611 males with K11_POSTOPDIS died.
Mortality risk
Mortality risk for people of age
years, who have K11_POSTOPDIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.178% | 0.422% |
| 5 | 1.108% | 2.41% |
| 10 | 2.726% | 6.275% |
| 15 | 5.339% | 11.542% |
| 20 | 8.65% | 18.715% |
Relationships between endpoints
↥Index endpoint: K11_POSTOPDIS – Postprocedural disorders of digestive system, not elsewhere classified
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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