No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1573 |
4. Check minimum number of eventsNone |
1573 |
5. Include endpointsNone |
1573 |
6. Filter based on genotype QC (FinnGen only) |
1522 |
Control definitions (FinnGen only)
Control exclude
K11_ORAL
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Cysts of oral region, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Diseases of oral cavity, salivary glands and jaws
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13659 | 5706 | 7899 |
| Only index persons | 12922 | 5483 | 7439 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.16 | 0.22 |
| Only index persons | 0.25 | 0.20 | 0.28 |
| Median age at first event (years) | |||
| Whole population | 47.71 | 48.23 | 47.37 |
| Only index persons | 47.53 | 48.20 | 47.03 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1522 | 665 | 857 |
| Unadjusted period prevalence (%) | 0.36 | 0.26 | 0.43 |
| Median age at first event (years) | 53.39 | 51.29 | 55.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_ORALCYST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORALCYST | 1.033 [0.91, 1.17] | 0.615 |
| Birth year | 0.995 [0.99, 1.0] | 0.232 |
During the follow-up period (1.1.1998 — 31.12.2019), 424 out of 4486 females with K11_ORALCYST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORALCYST | 1.224 [1.09, 1.38] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 795 out of 6006 males with K11_ORALCYST died.
Mortality risk
Mortality risk for people of age
years, who have K11_ORALCYST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.11% | 0.238% |
| 5 | 0.651% | 1.432% |
| 10 | 1.674% | 3.609% |
| 15 | 3.19% | 6.928% |
| 20 | 5.373% | 11.139% |
Relationships between endpoints
↥Index endpoint: K11_ORALCYST – Cysts of oral region, not elsewhere classified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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